Ningbo son-in-law with cancer for 30 years at home and abroad for the benefit of Sike about 700000 p winavi

Ningbo son-in-law with cancer for 30 years at home and abroad for the benefit of Sike about 700000 Xie Tian was awarded the HLHL fund with science and technology innovation award. (21) in the afternoon of the Propaganda Department of Hangzhou Normal University, Beijing Diaoyutai State Guest House held a grand prize awarding ceremony. The "China prize" of the HLHL prize, 2016 annual science and technology innovation award certificate to the Hangzhou Normal University Professor Xie tian. Evaluation & Selection Committee of the fund is: "Xie Tian Professor team has made great achievements in scientific research has originality, anticancer drug elemene liposome successfully developed with independent intellectual property rights and rare and Endangered Medicinal Dendrobium artificial breeding and cultivation technology, and achieve the promotion of industrialization, especially for the pharmaceutical industry plays an important role in the innovation and development of Chinese medicine industry." On the eve of the award ceremony, our reporter interviewed him. Break the "eight Zhes" in Zhejiang Wuyi Tian Xie anti-cancer secret, the science of medicine, master of traditional Chinese medicine, doctor of pharmacy research, Ningbo Cicheng Ji "Jiangnan famous doctor", honorary president of Zhejiang Province Traditional Chinese Medical Hospital professor Wei Changchun (the last century from 30s to 80s in Ningbo household’s grandson, Wei Zhiping of Zhejiang Chinese Medicine University) the professor’s son-in-law, Ningbo has repeatedly to do academic lectures, research Ningbo, Zhejiang Fritillaria, Dendrobium, figwort, Ophiopogon japonicus and other Chinese herbal medicines. Xie Tian during graduate school, his mother died of cancer. Then, his brother because of chronic deterioration of liver cancer surgery, less than half a year after the death of. He still remember that sentence, said to him: "brother brother before surgery to save me." At that time (most of the time), cancer therapy generally focused on the eradication of cancer, and the use of surgery, radiotherapy, chemotherapy and other means to control tumors. The drawback of this method is that the chemotherapy drug itself is toxic. Killing cancer cells can also damage normal cells. There is no one can kill cancer cells without harming normal cells of the body of the anticancer drug? Based on this starting point, Xie Tian 30 years ago to make a pledge: "we must develop efficient non-toxic anti-cancer drug!" in order to find the high efficiency and low toxicity of traditional Chinese medicine in the tens of thousands of species in Chinese medicine, Xie Tian repeated screening, repeated experiments. Finally, he in the "eight Zhes" (referring to the white atractylodes rhizome, Radix Paeoniae Alba, Zhejiang Fritillaria, Hang Baiju, Rhizoma Corydalis, Radix Scrophulariae, Radix Ophiopogonis, Radix Curcumae wenyujin) of the (also called Wen Eshu) found a highly efficient non-toxic anti-cancer material of volatile oil extraction, and innovative use of green technology to extract anticancer activity component of elemene. To benefit about 700000 cancer patients both at home and abroad, "at first we wanted to make water needles, but elemene was not soluble in water unless we added a large amount of toxic excipients. So what’s the difference between chemotherapy and other drugs?" Xie Tian said. Looking into the dead end, a name called liposome preparation goes into the R & D team. The raw material of this preparation is soybean lecithin (used as tofu) and cholesterol, which is safe and harmless to human body. But in the 80s and 90s of the last century, liposomes were still a concept, and no one in the world realized industrial production. Thanks to the difficulties of Xie Tian team, the first production line of liposome targeting formulation has been designed and manufactured. The fourth generation of drugs is the first time in our country.

宁波女婿跟癌症死磕30年 造福国内外70多万患者谢恬被授予何梁何利基金科学与技术创新奖。(杭州师范大学宣传部供图)21日下午,北京钓鱼台国宾馆举行了一次隆重颁奖典礼。有“中国诺贝尔奖”之称的何梁何利奖,将2016年度科学与技术创新奖证书交给了杭州师范大学教授谢恬。何梁何利基金评选委员会的评价是:“谢恬教授团队取得了具有原创性的重大科研成果,研发成功具有自主知识产权的抗癌新药榄香烯脂质体以及濒危珍稀中药材石斛人工繁育栽培技术,并实现产业化推广,对医药产业尤其是中药产业创新发展具有重要意义。”在颁奖典礼前夕,本报记者采访了他。破解“浙八味”里的抗癌秘密谢恬是浙江武义人,本科学西医,硕士学中医,博士研究中药学,是宁波慈城籍“江南名医”、浙江省中医院名誉院长魏长春教授(上世纪30年代至80年代在宁波家喻户晓)的孙女婿、浙江中医药大学魏治平教授的女婿,曾多次来甬做学术讲座,调研宁波的浙贝母、铁皮石斛、玄参、麦冬等中药材。谢恬读研期间,母亲罹患癌症去世。接着,他的师弟由于慢性肝炎恶化为肝癌,手术后不到半年过世。至今他还记得,师弟手术前对他说的那句话:“师兄救救我。”那个时候(目前多数也是),癌症疗法,一般都侧重于消灭肿瘤,采用手术、放疗、化疗等手段控制肿瘤。这种方法的缺陷在于,化疗药物本身就是有毒性的。杀灭癌细胞的同时,也会伤害正常细胞。有没有一种既能杀死癌细胞,又不伤害机体正常细胞的抗癌新药呢?基于这样的出发点,谢恬30年前给自己定下一个誓言:“一定要研发出高效无毒的抗癌新药!”为了能在上万种中药里找到高效低毒的抗癌中药,谢恬反复筛选,反复实验。最终,他在“浙八味”(指白术、白芍、浙贝母、杭白菊、延胡索、玄参、麦冬、温郁金)之一的温郁金(也叫温莪术)提取的挥发油中发现了高效无毒的抗癌活性物质,并创新采用绿色环保工艺提取分离出抗癌活性成分———榄香烯。造福国内外70多万癌症患者“起先我们想做成水针,但榄香烯不溶于水,除非我们加入大量有毒性的辅料增溶剂。可这样一来,跟别的化疗药物又有什么区别?”谢恬说。眼看着就要走进死胡同,一种名叫脂质体的制剂进入研发团队视线。这种制剂的原料为大豆磷脂(可用来做豆腐)和胆固醇,对人体安全无害。但在上世纪八九十年代,脂质体还是一个概念,在全球都没人实现过产业化生产。谢恬团队迎难而上,设计建成了全球首条脂质体靶向制剂产业化生产线,首次把第四代药物制剂的代表———脂质体运用于中药并成功产业化———把脂质体做成直径100纳米的圆球形外壳,里面包裹着高效低毒的抗癌活性成分榄香烯。脂质体天然亲癌细胞,当脂质体富集在癌细胞周围,进入癌细胞后,榄香烯就会“跑出来”消灭癌细胞了。榄香烯脂质体投产后,已使国内外70多万癌症患者受益。目前,平均每年有3万名左右患者在使用这种药。而其价格只有进口药物的1 3~1 2。这一重大医疗成果的出现立刻引发业界的关注,由谢恬领衔完成的“榄香烯脂质体系列靶向抗癌天然药物产业化技术及临床应用”获2012年度国家科技进步二等奖。两年后,谢恬又获得了有着中国医学界“诺贝尔奖”之称的吴阶平医学奖的青睐。-名词解释何梁何利奖“何梁何利奖”即何梁何利基金设立的奖项,是由何善衡基金有限公司、梁銶琚、何添先生、利国伟先生的伟伦有限公司共同捐资,于1994年在香港注册成立的科技奖励基金。“何梁何利奖”分为科学与技术成就奖、科学与技术进步奖、科学与技术创新奖。按学科领域分设数学力学奖、物理学奖、化学奖、天文学奖、气象学奖、地球科学奖、生命科学奖、农学奖、医学药学奖、古生物学考古学奖和机械电力、电子信息、交通运输、冶金材料、化学工程、资源环保、工程建设技术奖等17个奖项。参评者须由院士或此前获此奖的专家提名。相关的主题文章: